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BornAgain2

Chlorovirus ATCV-1 * the stupid virus

Chlorovirus ATCV-1 is part of the human oropharyngeal virome and is associated with changes in cognitive functions in humans and mice
August 2014
http://www.pnas.org/content/111/45/16106.abstract

Significance
Human mucosal surfaces contain a wide range of microorganisms. The biological effects of these organisms are largely unknown. Large-scale metagenomic sequencing is emerging as a method to identify novel microbes. Unexpectedly, we identified DNA sequences homologous to virus ATCV-1, an algal virus not previously known to infect humans, in oropharyngeal samples obtained from healthy adults. The presence of ATCV-1 was associated with a modest but measurable decrease in cognitive functioning. A relationship between ATCV-1 and cognitive functioning was confirmed in a mouse model, which also indicated that exposure to ATCV-1 resulted in changes in gene expression within the brain. Our study indicates that viruses in the environment not thought to infect humans can have biological effects.

Abstract

Chloroviruses (family Phycodnaviridae) are large DNA viruses known to infect certain eukaryotic green algae and have not been previously shown to infect humans or to be part of the human virome. We unexpectedly found sequences homologous to the chlorovirus Acanthocystis turfacea chlorella virus 1 (ATCV-1) in a metagenomic analysis of DNA extracted from human oropharyngeal samples. These samples were obtained by throat swabs of adults without a psychiatric disorder or serious physical illness who were participating in a study that included measures of cognitive functioning. The presence of ATCV-1 DNA was confirmed by quantitative PCR with ATCV-1 DNA being documented in oropharyngeal samples obtained from 40 (43.5%) of 92 individuals. The presence of ATCV-1 DNA was not associated with demographic variables but was associated with a modest but statistically significant decrease in the performance on [b]cognitive assessments of visual processing and visual motor speed. We further explored the effects of ATCV-1 in a mouse model. The inoculation of ATCV-1 into the intestinal tract of 9–11-wk-old mice resulted in a subsequent decrease in performance in several cognitive domains, including ones involving recognition memory and sensory-motor gating.[/b] ATCV-1 exposure in mice also resulted in the altered expression of genes within the hippocampus. These genes comprised pathways related to synaptic plasticity, learning, memory formation, and the immune response to viral exposure.
BornAgain2

This article should clear things up...

http://www.independent.co.uk/news...re-stupid-discovered-9849920.html
Virus that 'makes humans more stupid' discovered
11/9/14

A virus that infects human brains and makes us more stupid has been discovered, according to scientists in the US.

The algae virus, never before observed in healthy people, was found to affect cognitive functions including visual processing and spatial awareness.

Scientists at Johns Hopkins Medical School and the University of Nebraska stumbled upon the discovery when they were undertaking an unrelated study into throat microbes.

Surprisingly, the researchers found DNA in the throats of healthy individuals that matched the DNA of a virus known to infect green algae.

Dr Robert Yolken, a virologist who led the original study, said: “This is a striking example showing that the ‘innocuous’ microorganisms we carry can affect behaviour and cognition.

“Many physiological differences between person A and person B are encoded in the set of genes each inherits from parents, yet some of these differences are fuelled by the various microorganisms we harbour and the way they interact with our genes.”

Of the 90 participants in the study, 40 tested positive for the algae virus. Those who tested positive performed worse on tests designed to measure the speed and accuracy of visual processing. They also achieved lower scores in tasks designed to measure attention.

Humans’ bodies contain trillions of bacteria, viruses and fungi. Most are harmless, but the findings of this research show that there some microbes can have a detrimental impact on cognitive functions, while leaving individuals healthy.

The study’s findings were published in the Proceedings of the National Academy of Sciences.
CJ

Ah sweah alla society all over the world today has dis STOOPID VIRUS!
Everyone is crazy!

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